Table 1.
Between-Group Comparisons of Characteristics in Girls and Boys at the Age of 6 Years
Characteristics | Girls, n = 197 | Boys, n = 308 | ||||
---|---|---|---|---|---|---|
Poor Control Group, n = 81 | Good Control Group, n = 116 | P value | Poor Control Group, n = 133 | Good Control Group, n =175 | P value | |
Height, cm | 112.4 ± 5.4, n = 37 | 114.1 ± 5.4, n = 28 | 0.2 | 114.3 ± 5.9, n = 61 | 114.6 ± 4.9, n = 41 | 0.8 |
Weight, kg | 19.1 ± 3.0, n = 36 | 20.1 ± 2.8, n = 28 | 0.2 | 19.4 ± 2.8, n = 60 | 20.8 ± 3.4, n = 40 | 0.0246* |
Body mass index, kg/m2 | 15.1 ± 1.6, n = 36 | 15.6 ± 1.4, n = 27 | 0.3 | 14.9 ± 1.4, n = 60 | 15.8 ± 2.0, n = 40 | 0.0057* |
Lung function tests | ||||||
FVC, L | 1.15 ± 0.24, n = 21 | 1.20 ± 0.33, n = 13 | 0.6 | 1.32 ± 0.31, n = 34 | 1.28 ± 0.24, n = 26 | 0.6 |
%FVC predicted, % | 92.4 ± 19.2, n = 21 | 100.0 ± 23.8, n = 13 | 0.3 | 90.3 ± 15.7, n = 34 | 90.4 ± 14.1, n = 26 | 1.0 |
FEV1, L | 0.90 ± 0.27, n = 21 | 0.93 ± 0.26, n = 13 | 0.6 | 0.94 ± 0.25, n = 35 | 1.09 ± 0.17, n = 26 | 0.1 |
%FEV1 predicted, % | 78.0 ± 22.6, n = 21 | 84.1 ± 20.7, n = 13 | 0.4 | 74.0 ± 15.1, n = 35 | 84.3 ± 11.6, n = 26 | 0.0048* |
FEV1/FVC ratio | 0.77 ± 0.13, n = 21 | 0.78 ± 0.12, n = 13 | 0.7 | 0.77 ± 0.14, n = 34 | 0.87 ± 0.11, n = 26 | 0.0047* |
No. of children with ventilatory patterns, n (%) | ||||||
Restrictive | 2 (9.5), n = 21 | 2 (15.4), n = 13 | 0.6 | 7 (20.6), n = 34 | 6 (23.1), n = 26 | 1.0 |
Obstructive | 7 (33.3), n = 21 | 4 (30.8), n = 13 | 1.0 | 13 (38.2), n = 34 | 2 (7.7), n = 26 | 0.0076* |
Mixed | 4 (19.1), n = 21 | 1 (7.7), n = 13 | 0.6 | 1 (2.9), n = 34 | 0 (0), n = 26 | 1.0 |
Notes: Data were expressed as mean ± SD and number (%) of children. The poor control group had significantly lower mean scores (± SD, points) of the asthma control level in girls (2.95 ± 0.46, n = 39) (P < 0.0001) and boys (3.16 ± 0.37, n = 67) (P < 0.0001) compared with the good control group (4.0, n = 30 and 4.0, n = 46, respectively) at the age of 6 years. n = number of children tested. *P < 0.05 for between-group comparisons.
Abbreviations: FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; SD, standard deviation.