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. 2022 Jun 20;15:855752. doi: 10.3389/fnmol.2022.855752

TABLE 1.

Protein ligands of CaMKII in the postsynaptic compartment of glutamatergic synapses.

Sl. No. Protein ligand to which CaMKII binds Region of binding Functional implications of this binding Reference(s)
1 NMDAR subunit GluN2B 839–1120 The binding requires auto phosphorylated CaMKII; tethering at the synaptic membrane; LTP Lisman et al., 2012
2 NMDAR subunit GluN2B 1289–1310 Activated CaMKII can bind; tethering at the synaptic membrane; LTP Lisman et al., 2012
3 NMDAR subunit GluN2A 1349–1464 Synaptic targeting Gardoni et al., 1999
4 NMDAR subunit GluN1 845–863 Synaptic targeting Leonard et al., 2002
5 Cav1.2 1589–1690 Tethering at the synaptic membrane Hudmon et al., 2005
6 Densin-180 1247–1495 Membrane localization Strack et al., 2000b; Robison et al., 2005
7 Tiam 1 1540–1560 Constitutive CaMKII activation; LTP Saneyoshi et al., 2019
8 Ether-a-go-go (Eag) 731–803 Constitutive CaMKII activation; LTP Sun et al., 2004