Table 3.
Results of signal type prediction; cross-validation
| DeepLoc 2.0 | Specialized | ||
|---|---|---|---|
| ESM1b | ProtT5 | Predictor | |
| MicroF1 | 0.87 ± 0.01 | 0.87 ± 0.02 | |
| MacroF1 | 0.80 ± 0.02 | 0.80 ± 0.03 | |
| Accuracy | 0.78 ± 0.02 | 0.79 ± 0.03 | |
| MCC per signal (↑ is better) | |||
| SP | 0.89 ± 0.03 | 0.90 ± 0.03 | 0.87 ± 0.02 (32) |
| TM | 0.71 ± 0.07 | 0.66 ± 0.05 | - |
| MT | 0.93 ± 0.02 | 0.93 ± 0.03 | 0.94 ± 0.04 (33) |
| CH | 0.85 ± 0.07 | 0.86 ± 0.09 | 0.96 ± 0.03 (33) |
| TH | 0.86 ± 0.08 | 0.80 ± 0.08 | 0.98 ± 0.04 (33) |
| NLS | 0.65 ± 0.06 | 0.66 ± 0.01 | - |
| NES | 0.49 ± 0.20 | 0.46 ± 0.17 | - |
| PTS | 0.85 ± 0.06 | 0.90 ± 0.05 | - |
| GPI | 0.85 ± 0.06 | 0.86 ± 0.06 | 0.91 ± 0.01 (34) |
SP = Signal Peoptide, TM = First transmembrane domain, MT = Mitochondrial transit peptide , CH = Chloroplast transit peptide, TH = Thylakoidal transit peptide, NLS = Nuclear localization signal, NES = Nuclear export signal, PTS = Peroxisomal targeting signal, GPI = GPI-anchor