Table 2.
Causes of deaths among patients with haematologic cancers.
| Causes of death | Cancer | General population | SMR (95% CI) | ||
|---|---|---|---|---|---|
| Observed No. of deaths (%) | Mortality rates in cancer patients | Expected No. of deaths | Mortality rates in general population | ||
| All causes | 390,534 (100%) | 10,399.9 | NA | NA | NA |
| Index cancer | 219,731 (56%) | 5833.7 | NA | NA | NA |
| Non-index cancer | 57,631 (15%) | 1534.7 | NA | NA | NA |
| Non-cancer causes | 113,172 (29%) | 3004.6 | 45176.4 | 1199.4 | 2.51 (2.49–2.52) |
| Infections | 19,111 (5%) | 507.4 | 2933.4 | 77.9 | 6.51 (6.42–6.61) |
| Pneumonia and influenza | 5748 (2%) | 152.6 | 1609.8 | 42.7 | 3.57 (3.48–3.66) |
| Syphilis | 1 (0.0003%) | 0.03 | 0.8 | 0.02 | 1.19 (0.17–8.44) |
| Tuberculosis | 73 (0.02%) | 1.9 | 29.8 | 0.8 | 2.45 (1.95–3.08) |
| Septicemia | 2489 (1%) | 66.1 | 719.0 | 19.1 | 3.46 (3.33–3.60) |
| Other infections | 10,800 (3%) | 286.7 | 572.9 | 15.2 | 18.9 (18.5–19.2) |
| Cardio-vascular diseases | 49,498 (13%) | 1314.1 | 23825.7 | 632.5 | 2.08 (2.06–2.10) |
| Diseases of heart | 39,515 (10%) | 1049.1 | 18469.6 | 490.3 | 2.14 (2.12–2.16) |
| Hypertension without heart disease | 1353 (0.3%) | 35.9 | 467.4 | 12.4 | 2.89 (2.74–3.05) |
| Aortic aneurysm and dissection | 545 (0.1%) | 14.5 | 420.3 | 11.2 | 1.30 (1.19–1.41) |
| Atherosclerosis | 710 (0.2%) | 18.8 | 347.6 | 9.2 | 2.04 (1.90–2.20) |
| Cerebrovascular diseases | 6855 (2%) | 182.0 | 3871.4 | 102.8 | 1.77 (1.73–1.81) |
| Other diseases of arteries, arterioles, capillaries | 520 (0.1%) | 13.8 | 248.6 | 6.6 | 2.09 (1.92–2.28) |
| Respiratory diseases | 6405 (2%) | 170.0 | 3374.4 | 89.6 | 1.90 (1.85–1.95) |
| Chronic obstructive pulmonary disease and allied cond | 6405 (2%) | 170.0 | 3374.4 | 89.6 | 1.90 (1.85–1.95) |
| Gastrointestinal diseases | 1746 (0.4%) | 46.4 | 866.6 | 23.0 | 2.01 (1.92–2.11) |
| Stomach and duodenal ulcers | 366 (0.1%) | 9.7 | 122.5 | 3.3 | 2.99 (2.70–3.31) |
| Chronic liver disease and cirrhosis | 1380 (0.4%) | 36.6 | 743.9 | 19.7 | 1.86 (1.76–1.96) |
| Renal diseases | 3234 (0.8%) | 85.9 | 935.0 | 24.8 | 3.46 (3.34–3.58) |
| Nephritis, nephrotic syndrome and nephrosis | 3234 (0.8%) | 85.9 | 935.0 | 24.8 | 3.46 (3.34–3.58) |
| External injuries | 4717 (1%) | 125.2 | 2725.3 | 72.4 | 1.73 (1.68–1.78) |
| Accidents and adverse effects | 3620 (0.9%) | 96.1 | 1923.7 | 51.1 | 1.88 (1.82–1.94) |
| Suicide and self-inflicted injury | 958 (0.2%) | 25.4 | 586.5 | 15.6 | 1.63 (1.53–1.74) |
| Other cause of death | 28,461 (7%) | 755.6 | 10515.7 | 279.2 | 2.71 (2.68–2.74) |
| Homicide and legal intervention | 139 (0.04%) | 3.7 | 214.9 | 5.7 | 0.65 (0.55–0.76) |
| Alzheimer’s diseases | 2337 (0.6%) | 62.0 | 1191.0 | 31.6 | 1.96 (1.88–2.04) |
| Diabetes mellitus | 3115 (0.8%) | 82.7 | 1734.9 | 46.1 | 1.80 (1.73–1.86) |
| Congenital anomalies | 313 (0.1%) | 8.3 | 95.5 | 2.5 | 3.28 (2.93–3.66) |
| Certain conditions originating in perinatal period | 16 (0.004%) | 0.4 | 29.5 | 0.8 | 0.54 (0.33–0.88) |
| Complications of pregnancy, childbirth, puerperium | 54 (0.01%) | 1.4 | 3.0 | 0.1 | 17.7 (13.6–23.2) |
| Symptoms, signs and ill-defined conditions | 1498 (0.4%) | 39.8 | 614.8 | 16.3 | 2.44 (2.32–2.56) |
| Other cause of death | 21,128 (5%) | 560.9 | 6845.6 | 181.7 | 3.09 (3.05–3.13) |
The bold values are the indicate major groups.