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. 2022 Apr 2;25(4):218–223. doi: 10.1016/j.cjtee.2022.03.006

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — The expression of FASN in keloid (KS), hypertrophic scars (HS), and their dermal fibroblasts (NS). (A) As shown in full-thickness skin tissues, FASN expression was at lower levels in hypertrophic scars (∗∗∗∗p < 0.0001) and keloids (∗∗∗p = 0.0001) compared with that in normal skin. (B) The mRNA expression of FASN in KFBs (∗∗∗p = 0.0002) was higher than that in NFBs, while its expression in HFBs was decreased (∗∗∗p < 0.001). (C) There was no significant difference in protein expression of FASN between KFBs and NFB (p＞0.05), but it was downregulated in HFBs (∗p < 0.05).