Table 3.
Differential fatty acids of the full thickness between hypertrophic scar and normal skin.
| Metabolite | VIP | p value | Expressiona |
|---|---|---|---|
| Fatty acids | |||
| Ethylmethylacetic acid | 2.41 | 0.0001 | Down |
| Adrenic acid | 2.09 | 0.0019 | Up |
| Methylmalonic acid | 2.07 | 0.0021 | Up |
| Docosapentaenoic acid | 1.93 | 0.0048 | Up |
| Arachidonic acid | 1.90 | 0.0058 | Up |
| Eicosapentaenoic acid | 1.78 | 0.0108 | Up |
| Myristoleic acid | 1.72 | 0.0149 | Down |
| 2-Hydroxy-3-methylbutyric acid | 1.61 | 0.0238 | Up |
| Myristic acid | 1.58 | 0.0271 | Down |
| DPAn-6 | 1.55 | 0.0306 | Up |
| Palmitoleic acid | 1.55 | 0.0311 | Down |
| 12-Tridecenoic acid | 1.50 | 0.0372 | Down |
| Tridecanoic acid | 1.47 | 0.0413 | Down |
| Short-chain fatty acids | |||
| Succinic acid | 1.81 | 0.0096 | Up |
| Acetic acid | 1.74 | 0.0134 | Down |
VIP: variable influence on projection.
a
“down” means the expression of this fatty acid in hypertrophic scar was lower than that in normal skin; on the contrary, “up” means this fatty acid in hypertrophic scar was higher expression.