Table 3.
Factors associated with self-reported oral PrEP continuation at the final study visit (median of 3 months) among 131 women
| Characteristic | Total n (%) | Oral PrEP continuation at the final trial visit (median = 91 days) n (%) | Odds ratio (OR) (95% confidence interval [CI]) | p value | Adjusted OR (95% CI)a | p value | |
|---|---|---|---|---|---|---|---|
| Yes | No | ||||||
| Age > 24 years | 50 (38) | 40 (40) | 10 (31) | 1.49 (0.64, 3.48) | 0.36 | ||
| Age ≤ 24 years (ref) | 81 (62) | 59 (60) | 22 (69) | ||||
| Education (secondary level or higher) | 82 (63) | 62 (63) | 20 (63) | 1.01 (0.44, 2.29) | 0.99 | ||
| Education (secondary level—incomplete) (ref) | 49 (37) | 37 (37) | 12 (38) | ||||
| Relationship status | 0.35 | ||||||
| Lives with partner | 9 (7) | 8 (8) | 1 (3) | 2.76 (0.33, 22.92) | |||
| Does not live with partner (ref) | 121 (93) | 90 (92) | 31 (97) | ||||
| Earns an income | 22 (17) | 18 (18) | 4 (13) | 1.56 (0.48, 4.99) | 0.46 | ||
| Does not earn an income (ref) | 109 (83) | 81 (82) | 28 (88) | ||||
| STI diagnosis at enrolment | |||||||
| Chlamydia trachomatis detected | 32 (24) | 22 (22) | 10 (31) | 0.63 (0.26, 1.52) | 0.30 | ||
| Chlamydia trachomatis not detected (ref) | 99 (76) | 77 (78) | 22 (69) | ||||
| Neisseria gonorrhoea detected | 3 (2) | 3 (3) | 0 (0) | – | – | ||
| Neisseria gonorrhoea not detected (ref) | 128 (98) | 96 (97) | 32 (100) | ||||
| Unknown partner HIV status | 20 (15) | 14 (14) | 6 (19) | 0.71 (0.25, 2.04) | 0.53 | ||
| Partner is HIV-negative (ref) | 111 (85) | 85 (86) | 26 (81) | ||||
| More than 1 sex partner | 9 (7) | 4 (4) | 5 (16) | 0.23 (0.06, 0.91) | 0.04 | 0.24 (0.06, 0.97) | 0.05 |
| Has 0/1 sex partner (ref) | 122 (93) | 95 (96) | 27 (84) | ||||
| > 12 sex acts in the last 3 months | 17 (14) | 13 (14) | 4 (14) | 1.02 (0.30, 3.40) | 0.97 | ||
| ≤ 12 sex acts in last 3 months (ref) | 105 (86) | 80 (86) | 25 (86) | ||||
| Any unprotected sex in last 3 months | 88 (72) | 67 (72) | 21 (72) | 0.98 (0.39, 2.49) | 0.97 | ||
| No unprotected sex (always used condoms) (ref) | 34 (28) | 26 (28) | 8 (28) | ||||
| HIV risk perception | 0.21 (0.08, 0.55) | < 0.01 | |||||
| I will probably/definitely get infected with HIV | 30 (25) | 17 (18) | 13 (48) | 0.24 (0.10, 0.60) | < 0.01 | ||
| I will probably/definitely not get infected with HIV (ref) | 90 (75) | 76 (82) | 14 (52) | ||||
| Disclosed oral PrEP use | 118 (90) | 93 (94) | 25 (78) | 4.34 (1.34, 14.07) | 0.01 | 4.98 (1.45, 17.13) | 0.01 |
| Did not disclose oral PrEP use (ref) | 13 (10) | 6 (6) | 7 (22) | ||||
Bold values indicate p ≤ 0.05
aFactors associated with oral PrEP continuation at p < 0.05 are included in the multivariate analysis in which we adjust for a priori confounders (age (continuous) and relationship status)