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. 2021 Nov 17;43(7):1780–1792. doi: 10.1038/s41401-021-00797-z

Fig. 8. Schematic model of AC in attenuating adipose tissue inflammation.

Fig. 8

Therapeutically, AC activates SIRT1 to suppress the activation of NLRP3 inflammasome, which in turn alleviates macrophages and adipose tissue inflammation by reducing the secretion of IL-1β.