Table 7:
Comparison by body mass index
| RRSO | Control | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre-RRSO | Post-RRSO | Baseline | Follow-up | P1 | P2 | P3 | |||||||||||||
| BMI | BMI | BMI | BMI | ||||||||||||||||
| 18.5–<25kg/m2 | 25–<30kg/m2 | 30–<35kg/m2 | ≥35kg/m2 | 18.5–<25kg/m2 | 25–<30kg/m2 | 30–<35kg/m2 | ≥35kg/m2 | 18.5–<25kg/m2 | 25–<30kg/m2 | 30–<35kg/m2 | ≥35kg/m2 | 18.5–<25kg/m2 | 25–<30kg/m2 | 30–<35kg/m2 | ≥35kg/m2 | ||||
| N | 64 | 65 | 27 | 23 | 64 | 65 | 27 | 23 | 18 | 10 | 6 | 4 | 18 | 10 | 6 | 4 | |||
| Testosterone | 0.22 (0.15, 0.29) | 0.2 (0.17, 0.23) | 0.2 (0.16, 0.24) | 0.2 (0.15, 0.25) | 0.15 (0.12, 0.18) | 0.17 (0.13, 0.22) | 0.16 (0.09, 0.23) | 0.16 (0.09, 0.24) | 0.21 (0.15, 0.27) | 0.16 (0.12, 0.21) | 0.14 (0.08, 0.2) | 0.21 (0.1, 0.33) | 0.19 (0.15, 0.22) | 0.15 (0.12, 0.18) | 0.12 (0.06, 0.17) | 0.21 (0.08, 0.36) | 0.78 | <0.01 | 0.02 |
| Androstenedione | 0.58 (0.51, 0.66) | 0.52 (0.45, 0.59) | 0.49 (0.38, 0.61) | 0.48 (0.38, 0.58) | 0.49 (0.42, 0.56) | 0.46 (0.41, 0.52) | 0.45 (0.36, 0.54) | 0.45 (0.36, 0.55) | 0.54 (0.43, 0.66) | 0.49 (0.32, 0.69) | 0.42 (0.32, 0.53) | 0.38 (0.31, 0.45) | 0.51 (0.37, 0.65) | 0.43 (0.34, 0.53) | 0.36 (0.3, 0.43) | 0.38 (0.15, 0.64) | 0.77 | <0.01 | 0.85 |
| Androstenediol | 241.3 (213.3, 272.8) | 248.6 (210.1, 294.2) | 234.1 (177.5, 308.6) | 264.1 (213.3, 326.8) | 224.9 (191.2, 264.5) | 231.8 (190.2, 282.4) | 227.1 (167.7, 307.5) | 216 (173.0, 269.6) | 253.7 (189.4, 339.7) | 216.0 (157.2, 296.7) | 195.4 (116.7, 326.7) | 274.9 (164.7, 458.3) | 218.2 (165.9, 286.9) | 191.5 (130.9, 279.9) | 180.3 (100.9, 321.5) | 236.5 (129.6, 430.7) | 0.54 | <0.01 | 0.71 |
| Dihydrotestosterone | 36.7 (32.0, 42.0) | 32.1 (27.2, 37.9) | 27.8 (21.9, 35.2) | 26.1 (20.1, 33.8) | 31.8 (27.2, 37.1) | 29.9 (24.4, 36.5) | 23.8 (17.6, 32.0) | 20.1 (15.7, 25.7) | 41.5 (28.9, 59.4) | 28.7 (20.2, 40.5) | 21.6 (11.3, 40.6) | 32.1 (23.7, 43.4) | 38.3 (27.5, 53.0) | 26.7 (19.3, 36.7) | 19.1 (9.4, 37.7) | 28.1 (16.6, 46.9) | 0.14 | 0.05 | 0.69 |
| Androsterone | 115.7 (103.0, 130.0) | 112.3 (97.2, 129.8) | 104.6 (81.7, 134.0) | 113.4 (95.0, 135.4) | 98.5 (85.9, 112.8) | 111.2 (95.5, 129.4) | 116.9 (91.3, 149.7) | 101.5 (77.6, 132.7) | 125.5 (97.5, 161.3) | 92.7 (66.0, 129.9) | 102.5 (63.6, 165.0) | 125.5 (99.9, 157.4) | 105.7 (79.5, 140.4) | 113.4 (80.4, 159.9) | 87.2 (55.4, 137.1) | 112.3 (71.9, 175.1) | 0.75 | 0.06 | 0.39 |
| Dehydroepiandrosterone | 2.1 (1.8, 2.4) | 2.1 (1.8, 2.4) | 1.8 (1.4, 2.3) | 1.9 (1.5, 2.3) | 2.0 (1.7, 2.3) | 2.0 (1.7, 2.4) | 2.0 (1.5, 2.7) | 1.8 (1.4, 2.3) | 2.2 (1.6, 2.9) | 1.8 (1.2, 2.6) | 1.9 (1.2, 2.8) | 1.7 (1.1, 2.5) | 1.8 (1.4, 2.3) | 1.5 (1.0, 2.2) | 1.5 (0.8, 2.6) | 1.9 (1.2, 2.8) | 0.98 | <0.01 | 0.70 |
| Estrone | 16.3 (13.7, 19.4) | 18.7 (15.2, 22.9) | 23.8 (17.8, 31.6) | 28.4 (22.2, 36.2) | 14.0 (11.7, 16.8) | 18.1 (14.5, 22.5) | 16.8 (13.6, 20.8) | 24.0 (19.0, 30.3) | 20.1 (14.7, 27.4) | 15.6 10.3, 23.4) | 22.6 (17.0, 29.9) | 26.1 (15.3, 44.1) | 19.3 (13.5, 27.3) | 19.1 (12.7, 28.5) | 18.5 (10.4, 32.3) | 23.3 (11.4, 46.8) | 0.76 | <0.01 | 0.32 |
| Estradiol | 3.8 (2.7, 5.2) | 5.4 (3.8, 7.5) | 6.2 (3.8, 9.9) | 8.1 (6.0, 10.8) | 2.4 (1.9, 3.0) | 3.9 (3.0, 4.9) | 3.7 (2.9, 4.8) | 6.0 (4.6, 7.7) | 5.7 (3.1, 10.0) | 4.0 (2.6, 5.9) | 5.2 (3.9, 6.7) | 7.6 (3.5, 15.4) | 4.2 (1.9, 8.0) | 4.1 (2.5, 6.2) | 4.1 (2.5, 6.4) | 6.4 (3.3, 11.8) | 0.22 | <0.01 | 0.02 |
| SHBG | 96.5 (85.5, 109) | 62.4 (53.8, 72.4) | 48.4 (37.2, 62.8) | 35.6 (26.4, 47.9) | 98.5 (86.6, 112) | 64.4 (55.2, 75.0) | 44.6 (35.8, 55.5) | 36.7 (27.1, 49.6) | 103.6 (79.4, 135) | 60.6 (42.8, 85.6) | 54.1 (34.2, 85.3) | 65.7 (25.8, 165) | 102.5 (80.8, 130.1) | 59.9 (45.1, 79.6) | 58.1 (39.9, 84.5) | 63.7 (40.6, 99.6) | <0.01 | 0.80 | 0.14 |
P1: Body mass index; P2: Pre vs. Post; P3: RSSO vs. Controls