Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 4;5:85. doi: 10.1038/s41746-022-00618-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Schematic illustration of the five-step CPOP procedure with emphasis on the stable selection of features in Steps 3 and 4. b Quartile plot of the expression values of all genes (top panel) and all pairwise (bottom panel) log-ratio features for each sample (n = 488) in the melanoma data collection. Each sample is represented by the median (a single solid point), the first quartile (the lower end of a vertical line) and the third quartile (the upper end of a vertical line) of all the gene/feature values for that sample. c NanoString probe selection (186 probes) based on results from our previous microarray studies^7,14. d Scatter plot of log fold-change for genes common between MIA-Microarray and MIA-NanoString. e Boxplot comparisons of overall accuracy for overall survival (OS) and recurrence-free survival (RFS) between the MIA-Microarray and MIA-NanoString data. The y-axis shows the classification accuracy calculated from 100 repeated 5-fold cross-validation using a support vector machine classifier. The good/poor prognosis classes for overall survival (OS) and recurrence-free survival (RFS) are defined in Methods. The centreline of a boxplot denotes the median classification accuracy, and the lower and upper bounds of the box denote the first and third quartile values, respectively. The lower and upper whiskers denote 1.5 times the interquartile range away from the first and third quartile values, respectively.