Table 1.
Demographics and baseline characteristics
| Characteristic | Vehicle (n = 6) | OC-01 VNS (n = 12) | Total (N = 18) |
|---|---|---|---|
| Age (years) | |||
| Mean (SD) | 63.3 (13.46) | 60.5 (13.79) | 61.4 (13.35) |
| Range (min, max) | 39, 78 | 41, 86 | 39, 86 |
| Female, n (%) | 3 (50.0) | 11 (91.7) | 14 (77.8) |
| Race, n (%) | |||
| White | 6 (100) | 9 (75.0) | 15 (83.3) |
| Black or African American | 0 | 2 (16.7) | 2 (11.1) |
| Asian | 0 | 1 (8.3) | 1 (5.6) |
| Ethnicity, n (%) | |||
| Not Hispanic or Latino | 6 (100) | 11 (91.7) | 17 (94.4) |
| Not reported | 0 | 1 (8.3) | 1 (5.6) |
| Baseline clinical characteristics | |||
| STS (mm), mean (SD) | 4.5 (3.89) | 6.6 (4.42) | 5.9 (4.25) |
| Ocular Surface Disease Index score, mean (SD) | 44.0 (18.87) | 58.2 (21.85) | 53.5 (21.47) |
| Eye dryness score, mean (SD) | 66.3 (17.40) | 58.8 (26.69) | 61.3 (23.74) |
OC-01 VNS OC-01 (varenicline solution) nasal spray, SD standard deviation, min minimum, max maximum, STS Schirmer’s test score