TABLE 5.

The variances of AST and ALT levels in subgroups (ALT between 31 and 51 IU/L and gamma-GTP between 51 and 100 IU/L) by visit (PP Set).

Parameters	Treatment	Test	Mean ± SD	Placebo	Mean ± SD	p-value
		No.		No.
AST (GOT, IU/L)	Baseline (visit 1)	6	33.50 ± 4.55	11	29.27 ± 11.73
	6 weeks (visit 3)	6	29.33 ± 4.72	11	43.09 ± 44.69
	Change from baseline	6	-4.17 ± 8.50	11	13.82 ± 47.44	0.552
	p-value		0.2834		0.9414
	12 weeks (visit 4)	6	24.00 ± 2.53	11	28.27 ± 7.17
	Change from baseline	6	-9.50 ± 5.72	11	-1.00 ± 9.22	0.0511
	p-value		0.0096		0.7265
ALT (GPT, IU/L)	Baseline (visit 1)	6	40.50 ± 6.47	11	38.09 ± 6.70
	6 weeks (visit 3)	6	34.33 ± 12.60	11	41.00 ± 19.03
	Change from baseline	6	-6.17 ± 13.03	11	2.91 ± 20.95	0.4982
	p-value		0.2987		0.655
	12 weeks (visit 4)	6	25.67 ± 6.47	11	44.82 ± 17.28
	Change from baseline	6	-14.83 ± 5.04	11	6.73 ± 15.75	0.0088
	p-value		0.0313		0.3564