Fig. 3. Both neurogenesis and angiogenesis were promoted by catalpol.
a, c, d Neurogenesis in DG-SGZ and LV-SVZ was increased in catalpol groups. The number of DCX+/EdU+ double positive cells was significantly increased in ischemia brain after catalpol treatment for 14 days. b, e Angiogenesis was promoted by catalpol in the cortex. CD31+/EdU+ positive endothelial cells were significantly increased on day 14. Scale Bar = 100 μm. The data are presented as the mean ± S.D., n = 8, *P < 0.05, **P < 0.01.