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Gatekeeper CsgA mutants accelerate α-synuclein aggregation. Aggregation kinetics of Gatekeeper CsgA(CYGK CsgA) variants at 37 °C. A, CYGK CsgA. B, CDGK CsgA. Aggregation kinetics of α-synuclein alone or in the presence of CYGK CsgA variants. C, α-synuclein alone (blue) or in presence of CYGK CsgA (red). D, α-synuclein alone (blue) or in presence of CDGK CsgA (red). (Error bars represent SEM of three replicates). CYGK CsgA, CY Gatekeeper CsgA.
