Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 21;13:854239. doi: 10.3389/fphar.2022.854239

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Yao, Zhang, Ni, Ji, Hong, Chen, Wang, Li, Lin, Lu, Sheng, Sun, Shi, Zhou and Cai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

CEP suppressed the expression levels of matrix-degrading genes and inflammation-induced cartilage degradation. CEP-pretreated chondrocytes were incubated with IL-1β or TNF-α at 10 ng/ml for 24 h. (A) Gene expression analysis of MMP3, MMP9, MMP13, Adamts5, and iNOS in mouse chondrocytes treated with IL-1β or TNF-α. (B,C) Representative Western blots and quantification data of collagen II, iNOS, aggrecan, MMP9, Sox9, MMP3, and MMP13 in mouse chondrocytes after treatment with IL-1β or TNF-α, respectively. Values are expressed as mean ± SD, n = 3; #p < 0.05 vs. control group, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 vs. model group.