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Protective characteristics of CEP in a murine OA model. Immunofluorescence for antibody against collagen II and MMP13 (A), and quantitative analysis (B,C). Green, collagen II; Red, MMP13; Blue, DAPI. Scale bar = 20 μm. LD and HD represent the dose of 5 and 15 mg/kg CEP, respectively. Values are expressed as mean ± SD, n = 6. #p < 0.05 vs. sham group, **p < 0.01, ***p < 0.001, and ****p < 0.0001 vs. OA group.
