TABLE 1.
Baseline characteristics according to admission systolic blood pressure.
| All patients, n = 826 | SBP < 140, n = 244 | SBP ≥ 140, n = 582 | p-value | |
| Age-median (IQR) | 65 (57–74) | 64.5 (55–72) | 65 (58–74) | 0.094 |
| Sex | ||||
| Male-n (%) | 611 (74) | 183 (75) | 428 (73.5) | 0.663 |
| Female-n (%) | 215 (26) | 61 (25) | 154 (26.5) | … |
| Admission variables | ||||
| pc-ASPECTS-median (IQR) | 8 (7–9) | 8 (7–9) | 8 (6–9) | 0.246 |
| NIHSS-median (IQR) | 27 (16–33) | 26.5 (15–34) | 27 (17–33) | 0.771 |
| SBP-median (IQR) | 151 (135–169) | 126 (120–133) | 160 (150–177) | … |
| DBP-median (IQR) | 85 (78–98) | 79 (70–84) | 90 (80–100) | … |
| MAP-median (IQR) | 107 (98–119) | 94 (87–99) | 113 (106–124) | … |
| Serum glucose-median (IQR) | 7.9 (6.3–8.8) | 7.4 (5.9–8.5) | 8.2 (6.4–8.9) | 0.01 |
| Medical history | ||||
| Smoking-n (%) | 277 (33.5) | 85 (34.8) | 192 (33) | 0.608 |
| Drinking-n (%) | 182 (22) | 61 (25) | 121 (20.8) | 0.183 |
| Diabetes mellitus-n (%) | 187 (22.6) | 48 (19.7) | 139 (23.9) | 0.187 |
| Hypertension-n (%) | 583 (70.6) | 134 (54.9) | 449 (77.1) | <0.001 |
| Hyperlipidemia-n (%) | 281 (34) | 69 (28.3) | 212 (36.4) | 0.024 |
| Atrial fibrillation-n (%) | 160 (19.4) | 68 (27.9) | 92 (15.8) | <0.001 |
| Coronary heart disease-n (%) | 132 (16) | 38 (15.6) | 94 (16.2) | 0.836 |
| Ischemic stroke-n (%) | 186 (22.5) | 54 (22.1) | 132 (22.7) | 0.863 |
| Pre-stroke modified Rankin Scale score-n (%) | 0.792 | |||
| 0 | 697 (84.4) | 206 (84.4) | 491 (84.4) | |
| 1 | 86 (10.4) | 27 (11.1) | 59 (10.1) | |
| 2 | 43 (5.2) | 11 (4.5) | 32 (5.5) | |
| Stroke causative mechanism-n (%) | <0.001 | |||
| Large artery atherosclerosis | 536 (64.9) | 129 (52.9) | 407 (69.9) | |
| Cardio embolism | 205 (24.8) | 84 (34.4) | 121 (20.8) | |
| Other | 85 (10.3) | 31 (12.7) | 54 (9.3) | |
| Occluded segment-n (%) | 0.058 | |||
| Basilar artery distal | 267 (32.3) | 94 (38.5) | 173 (29.7) | |
| Basilar artery middle | 292 (35.4) | 84 (34.4) | 208 (35.7) | |
| Basilar artery proximal | 121 (14.6) | 32 (13.1) | 89 (15.3) | |
| Vertebral artery-v4 segment | 146 (17.7) | 34 (13.9) | 112 (19.2) | |
| Collaterals-n (%) | 0.255 | |||
| Grade 0 | 200 (24.2) | 56 (23) | 144 (24.7) | |
| Grade 1 | 306 (37) | 97 (39.8) | 209 (35.9) | |
| Grade 2 | 213 (25.8) | 55 (22.5) | 158 (27.1) | |
| Grade 3 | 106 (12.8) | 35 (14.3) | 71 (12.2) | |
| Grade 4 | 1 (0.1) | 1 (0.4) | 0 | |
| Treatments profiles | ||||
| Intravenous alteplase-n (%) | 165 (20.0) | 55 (22.5) | 110 (18.9) | 0.233 |
| Time from stroke onset to imagine diagnosis, minutes-median (IQR) | 205 (88–356) | 209.5 (82.8–357.8) | 201.5 (89.8–352) | 0.89 |
| Time from stroke onset to treatment, minutes-median (IQR) | 245 (129.8–393.3) | 249.5 (123.5–393) | 240 (132–393.3) | 0.932 |
Hypertension, diabetes mellitus, atrial fibrillation, coronary artery disease, ischemic stroke, and hyperlipidemia were defined by self-reported history. DBP, diastolic blood pressure; SBP, systolic blood pressure; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; and pc-ASPECT, Posterior Circulation-Alberta Stroke Program Early CT Score.