TABLE 2.
Outcomes according to admission systolic blood pressure.
| All patients, n = 826 | SBP < 140 mm Hg, n = 244 | SBP ≥ 140 mm Hg, n = 582 | p-value a | |
| Primary outcome | ||||
| mRS score at 90 day, median (IQR) | 6 (3, 6) | 5 (2, 6) | 6 (4,6) | 0.001 |
| Secondary outcomes | ||||
| mRS score 0–1 at 90 day, n (%) | 144 (17.4) | 56 (23) | 88 (15.1) | 0.007 |
| mRS score 0–2 at 90 day, n (%) | 190 (23) | 75 (30.7) | 115 (19.8) | 0.001 |
| mRS score 0–3 at 90 day, n (%) | 224 (27.1) | 85 (34.8) | 139 (23.9) | 0.001 |
| Mortality at 90 day, n (%) | 426 (51.6) | 107 (43.9) | 319 (54.8) | 0.004 |
| Successful reperfusion, n (%)b | 531 (64.3) | 181 (74.2) | 350 (60.1) | <0.001 |
| TICI score, n (%) | <0.001 | |||
| 0 | 219 (26.5) | 38 (15.6) | 181 (31.1) | |
| 1 | 14 (1.7) | 3 (1.2) | 11 (1.9) | |
| 2A | 62 (7.5) | 22 (9) | 40 (6.9) | |
| 2B | 132 (16) | 41 (16.8) | 91 (15.6) | |
| 2C | 110 (13.3) | 33 (13.5) | 77 (13.2) | |
| 3 | 289 (35) | 107 (43.9) | 182 (31.3) | |
| NIHSS at 24 h, median (IQR) | 29 (14, 35) | 27.5 (11, 35) | 29 (16,35) | 0.122 |
| NIHSS score change from baseline at 24 h, median (IQR) | 0 (–2, 3) | 0 (–5, 2) | 0 (–2,4) | 0.018 |
| NIHSS score change from baseline at 5–7 days, median (IQR) | 0 (–8, 4) | –2 (–12, 2) | 0 (–6,4) | 0.002 |
| Symptomatic intracranial hemorrhage, n (%) | 46 (5.6) | 13 (5.5) | 33 (5.7) | 0.915 |
IQR, interquartile range; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure; and TICI, Thrombolysis in Cerebral Infarction.
aP value for difference between the 2 SBP groups: SBP ≥ 140 vs. SBP < 140.
bSuccessful reperfusion indicates scores TICI 2B, 2C, or 3.