TABLE 5.
Outcomes according to admission diastolic blood pressure.
| All patients, n = 826 | DBP < 90 mm Hg, n = 483 | DBP ≥ 90 mm Hg, n = 343 | p-valuea | |
| Primary outcome | ||||
| mRS score at 90 day, median (IQR) | 6 (3,6) | 5 (2,6) | 6 (4,6) | 0.011 |
| Secondary outcomes | ||||
| mRS score 0–1 at 90 day, n (%) | 144 (17.4) | 98 (20.3) | 46 (13.4) | 0.01 |
| mRS score 0–2 at 90 day, n (%) | 190 (23) | 126 (26.1) | 64 (18.7) | 0.012 |
| mRS score 0–3 at 90 day, n (%) | 224 (27.1) | 144 (29.8) | 80 (23.3) | 0.039 |
| Mortality at 90 day, n (%) | 426 (51.6) | 233 (48.2) | 193 (56.3) | 0.023 |
| Successful reperfusion, n (%)b | 531 (64.3) | 322 (66.7) | 209 (60.9) | 0.09 |
| TICI score, n (%) | 0.08 | |||
| 0 | 219 (26.5) | 111 (23) | 108 (31.5) | |
| 1 | 14 (1.7) | 11 (2.3) | 3 (0.9) | |
| 2A | 62 (7.5) | 39 (8.1) | 23 (6.7) | |
| 2B | 132 (16) | 77 (15.9) | 55 (16) | |
| 2C | 110 (13.3) | 66 (13.7) | 44 (12.8) | |
| 3 | 289 (35) | 179 (37.1) | 110 (32.1) | |
| NIHSS at 24 h, median (IQR) | 29 (14, 35) | 28 (12, 35) | 30 (16, 35) | 0.427 |
| NIHSS score change from baseline at 24 h, median (IQR) | 0 (–2, 3) | 0 (–2, 2) | 0 (–2, 5) | 0.016 |
| NIHSS score change from baseline at 5–7 days, median (IQR) | 0 (–8, 4) | –2 (–11, 3) | 0 (–6, 6) | 0.002 |
| Symptomatic intracranial hemorrhage, n (%) | 46 (5.6) | 22 (4.7) | 24 (7) | 0.154 |
IQR, interquartile range; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; DBP, diastolic blood pressure; and TICI, Thrombolysis in Cerebral Infarction.
aP value for difference between the 2 DBP groups: DBP ≥ 90 vs DBP < 90.
bSuccessful reperfusion indicates scores TICI 2B, 2C, or 3.