Table 1.
Demographic and clinical characteristics of PLC patients from the four medical centers.
| Variable | Total(n = 15801) | Shanghai(n = 8515) | Beijing(n = 2561) | Nanning(n = 2813) | Wuwei(n = 1912) | P |
|---|---|---|---|---|---|---|
| Age (yr) | ||||||
| Medium (IQR) | 54 (46–62) | 54 (46–61) | 56 (48–63) | 51 (43–60) | 58 (49-66) | <0.001 |
| <40 | 1,562 (9.9) | 780 (9.2) | 206 (8.0) | 443 (15.7) | 133 (7.0) | <0.001 |
| 40–59 | 9,098 (57.6) | 5,113 (60.0) | 1,424 (55.6) | 1,664 (59.2) | 897 (46.9) | |
| ≥60 | 5,141 (32.5) | 2,622 (30.8) | 931 (36.4) | 706 (25.1) | 882 (46.1) | |
| Gender | ||||||
| Female | 2,519 (15.9) | 1,191 (14.0) | 468 (18.3) | 367 (13.0) | 493 (25.8) | <0.001 |
| Male | 13,282 (84.1) | 7,324 (86.0) | 2,093 (81.7) | 2,446 (87.0) | 1,419 (74.2) | |
| HBV | ||||||
| Negative | 2,999 (19.9) | 1,034 (12.4) | 1,095 (42.8) | 345 (12.3) | 525 (38.4) | <0.001 |
| Positive | 12,064 (80.1) | 7,293 (87.6) | 1,461 (57.2) | 2,467 (87.7) | 843 (61.6) | |
| HCV | ||||||
| Negative | 11,027 (96.6) | 7,860 (98.3) | 1,941 (91.1) | 739 (98.1) | 487 (91.5) | <0.001 |
| Positive | 386 (3.4) | 137 (1.7) | 190 (8.9) | 14 (1.9) | 45 (8.5) | |
| Cirrhosis | ||||||
| No | 7,357 (53.8) | 4,684 (55.2) | 500 (59.2) | 1,088 (39.5) | 1,085 (68.4) | <0.001 |
| Yes | 6,318 (46.2) | 3,803 (44.8) | 345 (40.8) | 1,668 (60.5) | 502 (31.6) | |
| AFP (ng/ml) | ||||||
| <20 | 4,940 (39.3) | 3,187 (37.9) | 820 (57.3) | 933 (34.2) | – | <0.001 |
| ≥20 | 7,618 (60.7) | 5,211 (62.1) | 611 (42.7) | 1,796 (65.2) | – | |
| Albumin (g/L) | ||||||
| ≥40 | 6,661 (69.6) | 5,577 (68.2) | 164 (48.7) | 920 (34.5) | – | <0.001 |
| <40 | 4,518 (40.4) | 2,595 (31.8) | 173 (51.3) | 1,750 (65.5) | – | |
| Total bilirubin (µmol/L) | ||||||
| ≤23 | 10,077 (88.9) | 7,530 (90.5) | 315 (92.1) | 2,232 (83.6) | – | <0.001 |
| >23 | 1,257 (11.1) | 792 (9.5) | 27 (7.9) | 438 (16.4) | – | |
| Direct bilirubin (µmol/L) | ||||||
| ≤8 | 8,976 (81.5) | 7,034 (84.5) | – | 1,942 (72.2) | – | <0.001 |
| >8 | 2,035 (18.5) | 1,288 (15.5) | – | 747 (27.8) | – | |
| Ascites | ||||||
| No | 11,205 (96.7) | 8,370 (98.4) | 474 (95.0) | 2,361 (91.6) | – | <0.001 |
| Yes | 381 (3.3) | 140 (1.6) | 25 (5.0) | 216 (8.4) | – | |
| BCLC stage | ||||||
| 0 | 472 (4.0) | 378 (4.5) | 69 (8.9) | 25 (1.0) | – | <0.001 |
| A | 4,906 (41.3) | 3,028 (35.9) | 633 (81.7) | 1,245 (48.5) | – | |
| B | 4,330 (36.7) | 3,699 (43.8) | 57 (7.3) | 574 (22.4) | – | |
| C | 2,076 (17.6) | 1,336 (15.8) | 16 (2.1) | 724 (28.2) | – | |
| Pathological type | ||||||
| HCC | 13,003 (93.0) | 8,056 (94.6) | 2,110 (82.4) | 2,759 (98.3) | 78 (83.0) | <0.001 |
| ICC | 607 (4.3) | 314 (3.7) | 282 (11.0) | 0 | 11 (11.7) | |
| CHC | 222 (1.6) | 145 (1.7) | 59(2.3) | 16 (0.6) | 2 (2.1) | |
| Others | 146 (1.0) | 0 | 110 (4.3) | 33 (1.2) | 3 (3.2) | |
Data are shown in n (%).