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. 2022 Jun 21;13:739999. doi: 10.3389/fneur.2022.739999

Table 3.

Peri-procedural rate of stroke or death with CAS compared to CEA in the largest randomized trials of symptomatic patients.

Randomized trial n 30/120 day
stroke or
death rate (%)
CAS excess OR/HR/RR, 95% CI P
CAS CEA
ICSS, 2010 (72) 1,713 8.5 4.7 HR 1.86 (1.26–2.74) 0.001
CREST-1, 2010 (65) 1,321 6.0 3.2 HR 1.89 (1.11–3.21) 0.02
SPACE-1, 2006 (73) 1,183 7.7 6.5 OR 1.19 (0.75–1.92)* 0.4
EVA-3S, 2006 (74) 527 9.6 3.9 RR 2.5 (1.2–5.1) 0.01
CAVATAS, 2010# (75) 504 10.0 10.0 OR 1.00 (0.56–1.81)* 0.98
Wallstent, 2001 (76) 219 12.1 4.5 OR 3.00 (1.01–8.61)* 0.046

Bolded font indicates trials with sufficient statistical power to compare the peri-procedural rate of stroke and death with CEA and CAS.

120 day event rates.

#90% were symptomatic.

*OR calculated from published raw data.