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. 2022 Jun 21;13:877924. doi: 10.3389/fphar.2022.877924

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Copyright © 2022 Biao, Chen, Liu, Wang, Han, Li and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DZD inhibited NLRP3 activation and pyroptosis in NAFLD rats. (A,B) Western blot analysis of NLRP3, caspase1, GSDMD and GSDMD-N. Data are shown as the mean ± SD, n = 3. (C) qRT-PCR analysis of NLRP3, caspase1, GSDMD and GSDMD-N. Data are shown as the mean ± SD, n = 6. Lowercase letters indicate statistically significant differences (p < 0.05) according to ANOVA followed by Tukey’s HSD test.