Table 2.
Patient characteristics of the rel cohort (n = 18)
| Patient no. | Age at primary diagnosis [months] | KMT2A-r partner | sex | HOXA9 ΔCT Mean |
IRX1 ΔCT Mean |
EGR3 ΔCT Mean |
ICOSLG ΔCT Mean |
|---|---|---|---|---|---|---|---|
| REZ1 | 1.3 | AFF1 | F | 2.016418 | 5.156435 | 2.832994 | 6.612465 |
| REZ2 | 2.9 | MLLT1 | M | 5.517492 | 6.952302 | 4.17735 | 7.647544 |
| REZ3 | 3.8 | AFF1 | F | 10.23312 | 2.528003 | 4.301431 | 5.388622 |
| REZ4 | 2.5 | AFF1 | F | 7.767597 | 2.621157 | 6.657438 | 4.662416 |
| REZ5 | 1.2 | AFF1 | F | 3.034274 | 6.716536 | 1.18892 | 5.421249 |
| REZ6 | 10.7 | MLLT1 | M | 7.759405 | 4.871906 | 5.178097 | 5.714579 |
| REZ7 | 4.3 | MLLT1 | M | −0.47106 | 4.344864 | 3.729839 | 2.899311 |
| REZ8 | 3.6 | MLLT3 | F | 6.206228 | 6.106342 | 4.742364 | 5.892561 |
| REZ9 | 9.1 | AFF1 | F | 10.72401 | 4.103871 | 2.276168 | 4.287584 |
| REZ10 | 0.7 | AFF1 | F | 8.609946 | 2.540371 | 1.63076 | 4.492456 |
| REZ11 | 4.4 | AFF1 | M | 3.047612 | 5.159082 | 6.565317 | 4.748623 |
| REZ12 | 4.2 | AFF1 | M | 1.789008 | 6.10047 | 5.030182 | 5.842515 |
| REZ13 | 2.0 | AFF1 | F | 10.53802 | 1.708041 | 2.584866 | 5.500404 |
| REZ14 | 3.1 | AFF1 | F | 11.73027 | 9.246894 | 8.439681 | 4.853207 |
| REZ15 | 7.6 | AFF1 | F | 7.390529 | 6.94658 | 7.833634 | 2.701138 |
| REZ16 | 6.7 | AFF1 | M | 7.300869 | 9.940318 | 9.541564 | 4.663118 |
| REZ17 | 5.3 | AFF1 | M | 4.871099 | 8.645488 | 9.86666 | 3.962195 |
| REZ18 | 7.2 | AFF1 | M | 14.54123 | 9.570634 | 6.724747 | 3.354452 |
All samples were taken from PB on the day of relapse diagnosis. Gene expression values are indicated as the ΔCT mean of three technical replicates. F = female, M = male