Table 2.
n | Genotype | Injected 13C‐Lys brain extract | Labeling duration brain donors (days) | Time point post‐injection (days) | Age (days) |
---|---|---|---|---|---|
3 | APPtg | APPtg, cohort 1 | 50, 100 | 1 | 51 |
3 | APPtg | non‐tg | 10 | 1 | 51 |
3 | APPtg | APPtg, cohort 1 | 50, 100 | 3 | 53 |
3 | APPtg | non‐tg | 10 | 3 | 53 |
3 | APPtg | APPtg, cohort 1 | 50, 100 | 5 | 55 |
3 | APPtg | non‐tg | 10 | 5 | 55 |
3 | APPtg | APPtg, cohort 1 | 50, 100 | 7 | 57 |
3 | APPtg | non‐tg | 10 | 7 | 57 |
3 | APPtg | APPtg, cohort 1 | 50, 100 | 10 | 60 |
3 | APPtg | non‐tg | 10 | 10 | 60 |
4 | APPtg | APPtg, cohort 2 | 125 | 25 | 75 |
4 | APPtg | non‐tg | 10 | 25 | 75 |
4 | APPtg | APPtg, cohort 2 | 125 | 50 | 100 |
4 | APPtg | non‐tg | 10 | 50 | 100 |
4 | APPtg | APPtg, cohort 2 | 125 | 75 | 125 |
4 | APPtg | non‐tg | 10 | 75 | 125 |
3 | APPtg | APPtg, cohort 1 | 50, 100 | 100 | 150 |
1 | APPtg | APPtg, cohort 2 | 125 | 100 | 150 |
4 | APPtg | non‐tg | 10 | 100 | 150 |
6 | APPtg | APPtg, cohort 4 | 100 | 1 | 51 |
6 | APPtg | non‐tg | 100 | 1 | 51 |
3 | non‐APPtg | APPtg, cohort 3 | 75 | 1 | 51 |
n = number of animals, genotype of injected animals, injected brain extract, number of days during which the donors of brains used for extract generation had received the 13C‐Lys diet, sacrifice time point after injection, age at death.