Table 5. Summary of response from 28 experts recommending ASA testing in male infertility patients.
Variable | Value | |
---|---|---|
Indications for ASA testinga | ||
Sperm agglutination | 24 (85.7) | |
Asthenozoospermia | 15 (53.6) | |
Failed IUI | 13 (46.4) | |
Failed IVF | 13 (46.4) | |
Other | 4 (14.3) | |
Antisperm antibody tested | ||
IgA | 3 (10.7) | |
IgG | 4 (14.3) | |
Both | 21 (75.0) | |
Technique for testing | ||
MAR test (indirect) | 18 (64.3) | |
Immunobead test (direct) | 8 (28.6) | |
Other | 2 (7.1) | |
Relevance of ASA testing | ||
Effective | 20 (71.4) | |
Neutral | 7 (25.0) | |
Very effective | 1 (3.6) | |
Biological fluid tested for ASAa | ||
Semen | 22 (78.6) | |
Seminal plasma | 8 (28.6) | |
Serum | 4 (14.3) | |
Cut-off value for abnormal ASA testing (%) | ||
>20 | 10 (35.7) | |
>40 | 10 (35.7) | |
>50 | 8 (28.6) | |
Frequency of the ASA test ordered | ||
Monthly | 12 (42.9) | |
Yearly | 9 (32.1) | |
Weekly | 7 (25.0) | |
Number of ASA testing ordered monthly | ||
1–5 | 24 (85.7) | |
6–9 | 0 (0.0) | |
10–15 | 2 (7.1) | |
>15 | 2 (7.1) | |
Initial recommendation in case of positive ASA test | ||
Steroids | 14 (50.0) | |
ART | 8 (28.6) | |
Sperm washing for IUI | 2 (7.1) | |
Other | 4 (14.3) |
Values are presented as number (%).
ASA: antisperm antibodies, IUI: intrauterine insemination, IVF: in vitro fertilization, IgA: immunoglobulin A, IgG: immunoglobulin G, MAR: mixed antiglobulin reaction, ART: assisted reproductive technology.
aMultiple options can be selected.