Figure 3.

Correlation of brain amyloid-β deposition and the amplitude of low-frequency BOLD signal fluctuations (sALFF) for “No physiological regression” Cluster #2 (Table 2). Depicted are scatterplots for each physiological/vascular regression procedure, left to right: (a) “no physiological regression”, (b) “WM/CSF regression”, (c) “WM/CSF/GS regression”, and (e) “aggressive AROMA”. Blue crosses represent the 33 subjects, using mean sALFF and mean AV45 within this cluster. The plots show reduced correlation strength from (a) to (d). Statistical p values were derived from 10,000 random permutations. For scatterplots of the remaining significant clusters see Supplementary Figures 2–5.