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. Author manuscript; available in PMC: 2022 Jul 5.
Published in final edited form as: Clin Sci (Lond). 2022 Jun 17;136(11):879–894. doi: 10.1042/CS20220117

Figure 1. SSHTN mice had increased M1 macrophages, decreased M2 macrophages, and inflammation in the gonads.

Figure 1.

SBP measures in (A) male and (B) female control and mice administered L-NAME in the drinking water for 2 weeks, then 2 weeks of tap water washout, and then 3 weeks of 4% salt diet (SSHTN) (n=6 in both males and females). Macrophage (M1 and M2) populations expressed as percentage of CD11b+F4/80+ cells in (C) testes and (D) ovaries from control and SSHTN mice, as determined by flow cytometry (n=8 in both males and females). Gene expression of proinflammatory mediators in (E) testes and (F) ovaries from control and SSHTN mice (n=6 in both males and females). Results are expressed as mean ± SEM, and statistical analysis consisted of a Student’s t test. *P<0.05 vs control.