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. Author manuscript; available in PMC: 2022 Jul 5.
Published in final edited form as: Clin Sci (Lond). 2022 Jun 17;136(11):879–894. doi: 10.1042/CS20220117

Figure 4. LHTN was associated with altered macrophage polarization and inflammation in the gonads.

Figure 4.

SBP measures in (A) male and (B) female control and mice administered L-NAME in the drinking water for 3 weeks (LHTN) (n=6 in both males and females). Macrophage (M1 and M2) populations expressed as percentage of CD11b+F4/80+ cells in (C) testes and (D) ovaries from control and LHTN mice, as measured by flow cytometry (n=8 in both males and females). Gene expression of proinflammatory mediators in (E) testes and (F) ovaries from control and LHTN mice (n=6 in both males and females). Results are expressed as mean ± SEM, and statistical analyses consisted of Student’s t test. *P<0.05 vs control.