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. 2022 Jun 27;19(3):314–321. doi: 10.4274/tjps.galenos.2021.88655

Figure 2.

Figure 2

Anti-proliferative effects of britannin on K562 and U937 cells. (A) Treatment of K562 and U937 cells with increasing concentrations of britannin led to a decrease in the DNA synthesis rate of the cells. (B) Britannin significantly increased the expression of p21 and p27 in both cell lines. Values are given as mean ± SD of three independent experiments

*p≤0.05 represent significant changes from untreated control, SD: Standard deviation