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. 2022 Jun 26;10(18):5965–5983. doi: 10.12998/wjcc.v10.i18.5965

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Hub module and hub miRNAs. A: Heat map of the correlation between module eigengene and psoriasis. The correlation between turquoise module and psoriasis was highest; B: Scatter plot of miRNAs in the turquoise module. MiRNAs with module connectivity > 0.8 and clinical trait relationship > 0.5 were selected as candidate hub miRNAs; C: The 10 intersecting miRNAs were identified as real hub miRNAs.