Table 3.
Kyoto Encyclopedia of Genes and Genomics function enrichment of differentially expressed mRNAs
|
Category
|
hsa
|
Term
|
Count
|
P
value
|
Genes
|
| KEGG_PATHWAY | hsa03320 | PPAR signaling pathway | 14 | 3.07E-06 | GK, MMP1, ADIPOQ, LPL, FADS2, ACADL, ACOX2, FABP5, FABP7, ACSBG1, PLIN1, ANGPTL4, SLC27A4, PPARD |
| KEGG_PATHWAY | hsa05164 | Influenza A | 22 | 1.05E-05 | NLRX1, RSAD2, DDX58, STAT1, TMPRSS4, MX1, MAPK13, PYCARD, CXCL10, SOCS3, OAS1, OAS2, IL-1B, OAS3, TNFSF10, IRF7, CCL2, PRSS3, KPNA2, PRSS2, MYD88, IRF9 |
| KEGG_PATHWAY | hsa05133 | Pertussis | 12 | 2.56E-04 | PYCARD, C1QB, CASP7, NOS2, CALML5, IL-1B, IRF1, IRF8, CALML3, FOS, MYD88, MAPK13 |
| KEGG_PATHWAY | hsa05162 | Measles | 16 | 4.14E-04 | DDX58, STAT1, MX1, CD3G, CD3D, OAS1, CCNE2, CCNE1, OAS2, IL-1B, OAS3, TNFSF10, IRF7, PRKCQ, MYD88, IRF9 |
| KEGG_PATHWAY | hsa04668 | TNF signaling pathway | 14 | 4.87E-04 | MLKL, CCL20, CXCL1, FOS, NOD2, SELE, MMP9, MAPK13, CXCL10, SOCS3, CASP7, IL-1B, CCL2, JUNB |
| KEGG_PATHWAY | hsa04062 | Chemokine signaling pathway | 19 | 7.44E-04 | LYN, CXCL9, CCL22, STAT1, CCL20, CXCR4, CXCL1, CXCL13, CXCL10, HCK, CCL8, PLCB4, CXCR2, RAC2, CCL2, CCR7, CCL19, CCL18, CCL27 |
| KEGG_PATHWAY | hsa04060 | Cytokine-cytokine receptor interaction | 21 | 0.002838 | CXCL9, IL20, IL4R, CCL22, CCL20, CXCR4, IL19, CXCL1, CXCL13, CXCL10, CCL8, IL-1B, CXCR2, TNFSF10, CCL2, CCR7, CCL19, IL7R, CCL18, CCL27, TNFRSF21 |
| KEGG_PATHWAY | hsa05160 | Hepatitis C | 14 | 0.003635 | DDX58, STAT1, IFIT1, CLDN1, MAPK13, SOCS3, OAS1, OAS2, IRF1, OAS3, CLDN8, IRF7, CLDN17, IRF9 |
| KEGG_PATHWAY | hsa00590 | Arachidonic acid metabolism | 9 | 0.003655 | PLA2G2F, HPGDS, GPX2, PLA2G4D, PLA2G2A, PLA2G3, ALOX12B, CYP2E1, CYP4F8 |
| KEGG_PATHWAY | hsa04110 | Cell cycle | 13 | 0.00555 | BUB1B, TTK, CDC6, CDC25B, CCNA2, CDC20, CCNB2, CCNB1, CCNE2, PTTG1, CCNE1, CDK1, MAD2L1 |
| KEGG_PATHWAY | hsa05142 | Chagas disease (American trypanosomiasis) | 11 | 0.011418 | C1QB, GNA15, PLCB4, NOS2, IL-1B, CCL2, CD3G, FOS, CD3D, MYD88, MAPK13 |
| KEGG_PATHWAY | hsa04114 | Oocyte meiosis | 11 | 0.017478 | CDC20, CCNB2, CCNB1, PTTG1, CALML5, CCNE2, CCNE1, CDK1, CALML3, MAD2L1, AURKA |
| KEGG_PATHWAY | hsa00592 | Alpha-Linolenic acid metabolism | 5 | 0.018996 | PLA2G2F, FADS2, PLA2G4D, PLA2G2A, PLA2G3 |
| KEGG_PATHWAY | hsa05168 | Herpes simplex infection | 15 | 0.020979 | DDX58, STAT1, TAP1, FOS, IFIT1, SOCS3, OAS1, OAS2, IL-1B, OAS3, IRF7, CDK1, CCL2, MYD88, IRF9 |
| KEGG_PATHWAY | hsa04380 | Osteoclast differentiation | 12 | 0.021031 | FOSL1, SOCS3, FCGR3B, STAT1, LCK, IL-1B, BLNK, ACP5, FOS, JUNB, IRF9, MAPK13 |
| KEGG_PATHWAY | hsa04064 | NF-kappa B signaling pathway | 9 | 0.028614 | LYN, BCL2A1, DDX58, LCK, IL-1B, BLNK, PRKCQ, CCL19, MYD88 |
| KEGG_PATHWAY | hsa04621 | NOD-like receptor signaling pathway | 7 | 0.028679 | PYCARD, IL-1B, CARD6, CCL2, CXCL1, NOD2, MAPK13 |
| KEGG_PATHWAY | hsa00591 | Linoleic acid metabolism | 5 | 0.031316 | PLA2G2F, PLA2G4D, PLA2G2A, PLA2G3, CYP2E1 |
| KEGG_PATHWAY | hsa00120 | Primary bile acid biosynthesis | 4 | 0.031945 | CYP39A1, CH25H, ACOX2, CYP7B1 |
| KEGG_PATHWAY | hsa00140 | Steroid hormone biosynthesis | 7 | 0.033377 | SULT2B1, HSD11B1, STS, HSD3B1, HSD17B2, CYP2E1, CYP7B1 |
| KEGG_PATHWAY | hsa01100 | Metabolic pathways | 64 | 0.037857 | ST6GALNAC1, GDA, GLDC, PIK3C2G, PYGL, HK2, SMPD3, IL4I1, HPGDS, PNP, ACADL, SPTLC2, KYNU, NAMPT, LIPG, HYAL4, PGM2, TK1, UPP1, AASS, PLA2G4D, ARG1, GPT2, AMPD3, NME1, ALDH3A1, PLCB4, ACOX2, CMPK2, ACSBG1, CYP2E1, IDO1, PLA2G3, ALOX12B, FUT2, CYP2C18, FUT1, FUT3, TYMP, HSD11B1, UGCG, RDH12, HSD17B2, RDH16, ATP6V0A4, XDH, HAO2, PLA2G2F, GALNT6, RRM2, GK, GCH1, NOS2, PLA2G2A, HSD3B1, CYP4F8, ALDH4A1, SQLE, HAL, AKR1B10, DHRS9, POLE2, POLR3G, HPSE |
| KEGG_PATHWAY | hsa05143 | African trypanosomiasis | 5 | 0.047416 | PLCB4, IL-1B, SELE, MYD88, IDO1 |