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(A) Illustration of the anticancer application of SPTP@UCNP-Rb-DOX in TNBC murine model by cascade amplification of chemo-PDT with systematic anti-tumor immunity. Analysis of CD4+ T cells (B) and CD8+ T cells and (C) proliferation in spleen tissues collected from all mice groups. Quantitative analysis of TNF-α, IL-6, and IL-10 from tumor lysis solution (D) and (E) in spleen lysis solution by the Elisa kit. Adapted with permission from 107, copyright 2020 American Chemical Society.
