Table 3.

Serum hormone levels and intraclass correlation coefficients in 21-hydroxylase deficiency patients treated at the Department of Endocrinology, Rigshospitalet, Denmark. Sample 1 and sample 2 – the two most recent blood samples collected on a stable dose of glucocorticoid treatment and with no changes in potential oestrogen supplementation or pregnancy. The mean levels of hormones assessed on the two different occasions did not significantly differ (all P - values >0.26).

	Sample 1 median (IQR)	Sample 2 median (IQR)	ICC (95% CI) all patients	ICC (95% CI) long-acting GC	ICC (95% CI) short-acting GC
17-OH, n  = 57	13.4 (5.7–37.2)	11.2 (3.2–34.3)	0.82 (0.69–0.89)	0.82 (0.61–0.92)	0.80 (0.59–0.90)
ASD, n  = 51	3.5 (1.0–6.6)	3.2 (1.2–6.8)	0.89 (0.80–0.94)	0.81 (0.54–0.92)	0.92 (0.83–0.96)
Testosterone, n  = 57	0.77 (0.35–1.54)	0.82 (0.31–1.64)	0.88 (0.79–0.93)	0.85 (0.66–0.93)	0.89 (0.77–0.95)
DHEAs, n  = 49	0.2 (0.1–1.6)	0.2 (0.1–1.8)	0.99 (0.98–0.99)	0.98 (0.96–0.99)	0.99 (0.97–0.99)

NR, normal range, 17-OH, 17-hydroxyprogesterone (NR: <10 nmol/L); ASD, androstenedione (NR: 2.4–8.9 nmol/L); testosterone (NR: 0.55–1.8 nmol/L); DHEAs: (NR: 1.2–9.5 µmol/L); IQR: interquartile range; ICC, intraclass correlation coefficient; GC, glucocorticoid.