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Table 2.

Effect of statins on serum IDOL and PCSK9 levels.

Baseline After treatment
Age, years 38 ± 13
Men/women, n 17/15
Statin intensity (high/moderate/low) 11/19/2
TC, mmol/L 8.2 ± 1.7  4.8 ± 1.0b
LDL-C, mmol/L 6.2 ± 1.6  2.9 ± 1.0b
TG, mmol/L 1.2 ± 0.6  1.0 ± 0.7a
HDL-C, mmol/L 1.4 ± 0.3 1.5 ± 0.4
IDOL, pg/mL 1419 (1096–2142) 1261 (1048–1650)a
PCSK9, ng/mL 203 (165–253) 295 (226–332)b

aP< 0.05 and bP< 0.001 against baseline, paired Student’s t-test.