Search terms for design  1    randomised controlled trial.sh. 2    randomization.sh. 3    exp clinical trials/ 4    (clin$ adj25 trial$).ti.ab 5    random$.ti.ab. 6    or/1‐5

Search terms for population  7    Ankle/ or Ankle Joint/ 8    ankle.af. 9    exp Osteoarthritis/ 10  exp Arthritis/ 11 (osteoarthritis or arthritis or arthrosis or osteoarthrosis or (degenerative adj3 (arthr$ or disease))).ti.ab. 12  7 or 8 13  9 or 10 or 11 14  12 and 13

Combining terms  15  6 and 14