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. 2022 May 27;19(6):975–985. doi: 10.7150/ijms.71840

Fig 1.

Fig 1

Biogenesis of circRNAs. A. The back-splicing circularization requires the help of the complementary sequences (ALU repeats and RCMs). B. RBP-mediated circularization. C. Lariat-driven circularization.