Table 1.
Comparison of clinical parameters between cases and controls
| All | No alcohol intake | Alcohol intake | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | p | Cases | Controls | p | Cases | Controls | p | |
| Number | 2325 | 2660 | – | 1424 | 1662 | – | 901 | 958 | – |
| Age, year (SD) | 60.7(11.7) | 59.5(11.4) | < 0.001 | 63.8(10.7) | 61.8(10.6) | < 0.001 | 56.0(11.6) | 55.5(11.5) | 0.287 |
| Sex, male (%) | 1657(71.2) | 1817(69.2) | 0.132 | 817(57.4) | 962(57.8) | 0.806 | 840(93.0) | 855(89.1) | 0.003 |
| BMI, Kg/M2 (SD) | 24.7(3.1) | 24.4(3.0) | < 0.001 | 24.6(3.3) | 24.2(2.9) | 0.004 | 25.0(2.9) | 24.8(3.1) | 0.096 |
| Waist/hip ratio(SD) | 0.88(0.08) | 0.88(0.08) | 0.187 | 0.87(0.09) | 0.87(0.09) | 0.528 | 0.90(0.07) | 0.89(0.07) | 0.298 |
| SBP, mmHg(SD) | 121.8(19.6) | 127.9(17.2) | < 0.001 | 122.3(20.2) | 127.8(17.6) | < 0.001 | 121.0(18.5) | 128.0(16.5) | < 0.001 |
| DBP, mmHg(SD) | 76.2(11.8) | 79.4(9.6) | < 0.001 | 76.1(11.8) | 78.9(9.6) | < 0.001 | 76.3(11.8) | 80.2(9.6) | < 0.001 |
| History of hypertension (%) | 884(38.0) | 594(22.6) | < 0.001 | 576(40.5) | 383(23.0) | < 0.001 | 308(34.1) | 211(22.0) | < 0.001 |
| Diabetes (%) | 273(11.7) | 81(3.1) | < 0.001 | 198(13.9) | 53(3.2) | < 0.001 | 75(8.3) | 28(2.9) | < 0.001 |
| Alcohol intake (%) | 903(38.8) | 960(36.6) | 0.108 | – | – | – | – | – | – |
| Current smoker (%) | 1013(43.6) | 763(29.1) | < 0.001 | 434(30.5) | 297(17.8) | < 0.001 | 579(64.3) | 466(48.6) | < 0.001 |
| Depression (%) | 465(20.0) | 247(9.4) | < 0.001 | 295(18.2) | 142(8.5) | < 0.001 | 206(22.8) | 105(10.9) | < 0.001 |
| Total cholesterol, mmol/L(SD) | 4.68(1.17) | 4.58(1.14) | 0.005 | 4.70(1.23) | 4.61(1.17) | 0.052 | 4.64(1.06) | 4.51(1.08) | 0.022 |
| Triglyceride, mmol/L(SD) | 1.62(1.07) | 1.70(1.10) | 0.021 | 1.61(1.03) | 1.68(1.10) | 0.100 | 1.64(1.14) | 1.74(1.09) | 0.089 |
| HDL, mmol/L(SD) | 1.04(0.32) | 1.10(0.35) | < 0.001 | 1.04(0.33) | 1.11(0.35) | < 0.001 | 1.04(0.31) | 1.07(0.35) | 0.089 |
| ApoA1, g/L(SD) | 1.28(0.27) | 1.40(0.31) | < 0.001 | 1.29(0.28) | 1.42(0.32) | < 0.001 | 1.28(0.25) | 1.38(0.31) | < 0.001 |
| ApoB, g/L(SD) | 0.88(0.26) | 0.83(0.23) | < 0.001 | 0.88(0.27) | 0.84(0.23) | < 0.001 | 0.87(0.24) | 0.83(0.22) | < 0.001 |
| ApoB/A1(SD) | 0.70(0.22) | 0.61(0.20) | < 0.001 | 0.71(0.22) | 0.61(0.20) | < 0.001 | 0.70(0.21) | 0.62(0.22) | < 0.001 |
SBP systolic blood pressure, DBP diastolic blood pressure, HDL high-density lipoprotein, ApoA1 apolipoprotein A1, ApoB apolipoprotein B