Table 2.
The Hardy–Weinberg equilibrium in all cases and controls, and the association of ALDH2 rs671 with acute myocardial infarction subjects
| ALDH2 rs671 | ||||||
|---|---|---|---|---|---|---|
| Case | Control | Total | ||||
| Genotype | Number | % | Number | % | Number | % |
| GG | 1537 | 66.11 | 1852 | 70.69 | 3389 | 68.53 |
| GA | 699 | 30.06 | 692 | 26.41 | 1391 | 28.13 |
| AA | 89 | 3.83 | 76 | 2.90 | 165 | 3.34 |
| Total | 2325 | 100 | 2620 | 100 | 4945 | 100 |
| HWp | 0.393 | 0.245 | 0.131 | |||
| G | 3773 | 81.14 | 4396 | 83.89 | ||
| A | 877 | 18.86 | 844 | 16.11 | ||
| Model | χ2 | OR (95% CI) | p | |||
| AA/GG | 4.674 | 1.411 (1.031–1.931) | 0.03062 | |||
| GA/GG | 9.507 | 1.217 (1.074–1.379) | 0.00205 | |||
| AA + GA/GG | 11.98 | 1.236 (1.096–1.394) | 0.00054 | |||
| AA/GA/GG | 12.709 | 1.206 (1.088–1.337) | 0.00037 | |||
| 13.239 | 1.212 (1.093–1.345) | 0.00027 | adjusted by sex,age,bmi | |||
| 14.952 | 1.229 (1.107–1.364) | 0.00011 | adjusted by sex,age,bmi,drink | |||
| 15.769 | 1.236 (1.114–1.373) | 0.00008 | adjusted by sex,age,bmi,drinktimes | |||
| 13.995 | 1.219 (1.099–1.352) | 0.00018 | adjusted by drink | |||
| 14.585 | 1.224 (1.104–1.359) | 0.00014 | adjusted by drinktimes | |||
| 5.467 | 1.148 (1.023–1.288) | 0.01938 | adjusted by sex,age,bmi,ApoB/ApoA1 | |||
| A/G | 12.994 | 1.211 (1.091–1.343) | 0.00031 | |||