Table 3.
The Hardy–Weinberg equilibrium in subjects with no alcohol intake among cases and controls, and the association of ALDH2 rs671 with acute myocardial infarction in no alcohol intake subjects
| ALDH2 rs671 | ||||||
|---|---|---|---|---|---|---|
| Case | Control | Total | ||||
| Genotype | Number | % | Number | % | Number | % |
| GG | 881 | 61.87 | 1126 | 67.75 | 2007 | 65.04 |
| GA | 478 | 33.57 | 475 | 28.58 | 953 | 30.88 |
| AA | 65 | 4.56 | 61 | 3.67 | 126 | 4.08 |
| Total | 1424 | 100 | 1662 | 100 | 3086 | 100 |
| HWp | 0.920 | 0.218 | 0.337 | |||
| G | 2240 | 78.65 | 2727 | 82.04 | ||
| A | 608 | 21.35 | 597 | 17.96 | ||
| Model | χ2 | OR (95% CI) | p | |||
| AA/GG | 2.841 | 1.362 (0.950–1.953) | 0.09187 | |||
| GA/GG | 10.2 | 1.286 (1.102–1.501) | 0.00140 | |||
| AA + GA/GG | 11.667 | 1.295 (1.116–1.502) | 0.00064 | |||
| AA/GA/GG | 10.973 | 1.236 (1.090–1.401) | 0.00092 | |||
| 11.705 | 1.247 (1.099–1.415) | 0.00062 | adjusted by sex,age,bmi | |||
| 5.44 | 1.182 (1.027–1.360) | 0.01968 | adjusted by sex,age,bmi,ApoB/ApoA1 | |||
| A/G | 11.206 | 1.240 (1.093–1.406) | 0.00082 | |||