Table 2.
Characteristics of Symptoms and Quality of Life Scores
| More Symptomatic (n = 201) | Less Symptomatic (n = 201) | |||
|---|---|---|---|---|
| Outcome measures | Parent Proxy Report (n = 201) | Child self-report (n = 159) | Parent Proxy Report (n = 201) | Child self-report (n = 167) |
| Proxy-SSPedi or Mini-SSPedi | ||||
| Median total SSPedi scores day 1 (IQR) | 14 (8 to 20) | 10 (4 to 18) | 3 (1 to 7) | 4 (1 to 8) |
| Mean total SSPedi scores day 1 (SD) | 14.8 ± 8.5 | 11.3 ± 9.8 | 5.1 ± 5.7 | 5.4 ± 5.9 |
| Median minutes completion day 1 (IQR)* | 2.0 (1.5 to 3.3) | 5.1 (3.8 to 6.5) | 1.6 (1.2 to 2.6) | 5.0 (4.2 to 6.2) |
| Day 4 sample size | (n = 191) | (n = 142) | NA | NA |
| Median total SSPedi scores day 4 (IQR) | 13 (7 to 18) | 6 (2 to 12) | ||
| Mean total SSPedi scores day 4 (SD) (n = 191) | 13.2 ± 8.2 | 8.2 ± 8.7 | ||
| Median minutes completion day 4 (IQR)* | 1.5 (1.1 to 2.2) | 3.8 (3.2 to 4.9) | ||
| Children’s International Mucositis Evaluation Scale | ||||
| Median ChIMES Scores (IQR) | 0 (0 to 2) | 0 (0 to 2) | 0 (0 to 0) | 0 (0 to 0) |
| Median ChIMES Percent (IQR) | 0 (0 to 8.7) | 0 (0 to 8.7) | 0 (0 to 0) | 0 (0 to 0) |
| Pediatric Nausea Assessment Tool, n (%) | ||||
| Nausea now | ||||
| No nausea at all | 132 (66.3%) | 132 (84.1%) | 191 (95.0%) | 153 (91.6%) |
| A little bit nauseated | 41 (20.6%) | 17 (10.8%) | 8 (4.0%) | 13 (7.8%) |
| Even more nauseated | 16 (8.0%) | 4 (2.5%) | 2 (1.0%) | 1 (0.6%) |
| Nauseated a whole lot | 10 (5.0%) | 4 (2.5%) | 0 (0.0%) | 0 (0.0%) |
| Vomited yesterday or today | 63 (31.5%) | 47 (29.7%) | 6 (3.0%) | 4 (2.4%) |
| Faces Pain Scale-Revised, median rating (IQR) | 0 (0 to 3.5) | 0 (0 to 2) | 0 (0 to 0) | 0 (0 to 0) |
| Global Quality of Life Categorical Scale, median (IQR) | 3 (2 to 3) | 1 (1 to 2) | 1 (1 to 2) | 1 (1 to 1) |
| Overall Symptom Scale, median (IQR) | 2 (2 to 3) | 1 (1 to 2) | 1 (1 to 1) | 1 (1 to 1) |
| Symptom change rating on day 4, No. (%) | NA | NA | ||
| Much worse | 34 (17.9%) | 90 (67.2%) | ||
| A little worse | 60 (31.6%) | |||
| The same | 45 (23.7%) | 28 (20.9%) | ||
| A little better | 38 (20.0%) | 16 (11.9%) | ||
| Much better | 13 (6.8%) | |||
* Available in n = 215 parents and n = 194 children who completed day 1 and n = 107 parents and n = 98 children who completed day 4 on an iPad
Abbreviations: IQR Interquartile range, NA Not applicable, SD Standard deviation