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. 2022 Jun 21;13:917905. doi: 10.3389/fimmu.2022.917905

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Copyright © 2022 Adjobimey, Meyer, Sollberg, Bawolt, Berens, Kovačević, Trudić, Parcina and Hoerauf

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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High neutralizing antibody expression in AstraZeneca- mRNA vaccine combinations. Graphs represent the expression of SARS-CoV-2 specific spike-protein binding IgG (A), IgA (B), and neutralizing antibody expression (C) observed in the sera of people that received homologous (AstraZeneca, Moderna, or BioNTech) ‘s COVID-19 vaccines or heterologous vaccine doses (AstraZeneca-Moderna or AstraZeneca-BioNTech). Each symbol represents individual donors. Indicated p values were calculated using Kruskal-Wallis ‘test followed by Dunn’s comparison post hoc to compare all groups. Bars represent the median (A, B) of SARS-CoV-2 spike protein-specific antibody expression in each group in arbitrary binding units (ABU) or the means ± SEM percentages of relative neutralizing antibody expression (C). Significance is accepted if p <0.05.