Figure 3.

Mucinous adenocarcinoma of the appendix with ovarian involvement. A,B: Axial CT scans, before and after intravenous contrast administration, showing a tubular structure corresponding to a distended appendix (solid arrow), with irregular wall thickening and enhancing mural nodularity (arrowhead), features that are suggestive of malignancy. A large, predominantly cystic lesion is also seen, apparently in the right ovary (dashed arrow). C,D: The final histopathologic diagnosis was a mucinous adenocarcinoma of the appendix with metastasis to the right ovary (haematoxylin and eosin; magnification, ×40). Atypical irregular glands (arrow) infiltrating the wall of the appendix (C) with a desmoplastic stromal response. Extracellular mucin (asterisk) composing more than 50% of the tumour. A similar neoplasm can be seen in the ovary (D), with a CK20+/CK7- phenotype, consistent with colorectal origin.