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. 2022 Jul 6;378:e069775. doi: 10.1136/bmj-2021-069775

Table 1.

Characteristics of SpO2-SaO2 pairs recorded in study population, by race and ethnic origin

Characteristics Non-Hispanic white Non-Hispanic black Hispanic/
Latino
P value of difference
White v black White v Hispanic
Paired SpO2-SaO2 readings
Total No 21 918 6498 1623
Median (IQR) pulse oximetry (SpO2, %) 95 (93-97) 97 (94-99) 97 (94-99) <0.001 <0.001
Median (IQR) arterial oxygen saturation (SaO2, %) 94 (89.9-96.6) 94.3 (89-97.1) 95 (90.2-98) 0.31 <0.001
Supplemental oxygen (L/min)
 Median (IQR) 0 0 0 <0.001 0.14
 Mean (SD) 0.9 (2.5) 0.6 (2.0) 0.8 (2.7) <0.001 0.14
Potential occult hypoxemia
 All SpO2 (92-100%) 18 157 (82.8) 5852 (90.1) 1466 (90.3) <0.001 <0.001
 SaO2 <88% if SpO2 is 92-100% 2823 (15.6) 1144 (19.6) 237 (16.2) <0.001 0.53
Patient day characteristics
Total No 20 822 6190 1519
Median (IQR) age (years) 69 (64-77) 66 (60-72) 68 (62-76) <0.001 <0.001
Male sex (No (%)) 20 099 (96.5) 5852 (94.5) 1479 (97.4) <0.001 0.082
Primary diagnoses (No (%))
 Chronic obstructive pulmonary disease 2984 (14.3) 681 (11.0) 97 (6.4) <0.001 <0.001
 Respiratory failure 2766 (13.3) 633 (10.2) 162 (10.7) <0.001 0.003
 Septicemia 1622 (7.8) 466 (7.5) 118 (7.8) 0.50 0.98
 Pneumonia 1608 (7.72) 291 (4.7) 59 (3.9) <0.001 <0.001
 Congestive heart failure 1336 (6.4) 464 (7.5) 84 (5.5) 0.003 0.17
 Coronary atherosclerosis 391 (1.9) 108 (1.7) 184 (12.1) 0.50 <0.001
 Diabetes with complication 309 (1.5) 204 (3.3) 30 (2.0) <0.001 0.13
 Cardiac dysrhythmia 361 (1.7) 94 (1.5) 18 (1.2) 0.25 0.11
 Renal failure 316 (1.5) 115 (1.9) 23 (1.5) 0.06 0.99
 Acute myocardial infarction 223 (1.1) 58 (0.9) 71 (4.7) 0.36 <0.001
 Other 8906 (42.8) 3076 (49.7) 673 (44.3) <0.001 0.24
Comorbidities* (No (%))
 Congestive heart failure 7304 (35.1) 2202 (35.6) 486 (32.0) 0.47 0.02
 Neurological disease 2436 (11.7) 896 (14.5) 175 (11.5) <0.001 0.834
 Chronic pulmonary disease 11 911 (57.2) 2642 (42.7) 495 (32.6) <0.001 <0.001
 Liver disease 1746 (8.4) 694 (11.2) 213 (14.0) <0.001 <0.001
 Diabetes without complication 5099 (24.5) 1732 (28.0) 448 (29.5) <0.001 <0.001
 Diabetes with complication 3480 (16.7) 1171 (18.9) 359 (23.6) <0.001 <0.001
 Non-metastatic cancer 2176 (10.5) 711 (11.5) 146 (9.6) 0.02 0.30
 Metastatic cancer 782 (3.8) 266 (4.3) 38 (2.5) 0.05 0.01
 Renal disease 4935 (23.7) 2004 (32.4) 447 (29.4) <0.001 <0.001
 Median (IQR) length of hospital stay (days) 6 (4-10) 6 (3-11) 9 (4-17) <0.001 <0.001
Mortality (No (%))
 In hospital 1118 (5.4) 350 (5.7) 91 (6.0) 0.39 0.30
 At 30 days 2240 (10.8) 553 (8.9) 142 (9.4) <0.001 0.086

SaO2=arterial blood gas reading; SpO2=pulse oximetry reading; IQR=interquartile range; SD=standard deviation.