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. 2022 Jun 6;9:rbac038. doi: 10.1093/rb/rbac038

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© The Author(s) 2022. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Three-dimensional bioprinting scaffold with NSCs and OLGs promoted myelinization and regeneration of axons. Immunofluorescence staining against NF (A), MBP (C) and 5-HT (E). A significantly higher number of axon (NF-positive cells, MBP-positive cells and 5-HT-positive cells) were observed at lesion site of SCI in cells/scaffold group compared with scaffold and SCI groups; 3D bioprinting sodium alginate/gelatin scaffold with NSCs and OLGs implantation showed successful remyelination of the regenerated nerve fibers. Quantifications of NF-positive cells (B), MBP-positive cells (D) and 5-HT-positive cells (F) in three groups.