Figure E2.

Change in LVEF by crossclamp time in aortic surgery patients that using the described del Nido dosing strategy after excluding patients with preoperative aortic insufficiency (A) or aortic stenosis (B) and subsequent aortic valve operation. On multivariable analysis, cross clamp time was not found to be a predictor for change in LVEF in the group without patients with corrected aortic insufficiency (coefficient estimate = 0.002; 95% CI, 0.988-1.016; P = .814) or corrected aortic stenosis (coefficient estimate = 0.004; 95% CI, 0.990-1.019; P = .566). LVEF, Left ventricular ejection fraction; CI, confidence interval.