Table E3.
Sensitivity analysis for patients missing LVEF data
| Variable | LVEF data (n = 432), N (%), median [IQR] | Missing LVEF data (n = 8), N (%), median [IQR] | P value |
|---|---|---|---|
| Preoperative characteristics | |||
| Age | 61 [50-69] | 60 [56-78] | .297 |
| Female | 98 (23) | 2 (25) | 1.000 |
| Body surface area | 2.04 [1.88-2.20] | 2.12 [1.93-2.23] | .636 |
| Hypertension | 319 (74) | 6 (75) | 1.000 |
| On dialysis | 5 (1) | 0 (0) | 1.000 |
| Diabetes | 60 (14) | 1 (13) | 1.000 |
| Infective endocarditis | 24 (6) | 1 (13) | .944 |
| Chronic lung disease | 54 (13) | 3 (38) | .120 |
| Cerebrovascular disease | 50 (12) | 0 (0) | .646 |
| Peripheral vascular disease | 102 (24) | 1 (13) | .753 |
| Preoperative LVEF | 60 [55-62] | 33 [33-55]∗ | .067 |
| Moderate or severe aortic stenosis | 60 (14) | 1 (13) | 1.000 |
| Moderate or severe aortic insufficiency | 116 (27) | 3 (38) | .787 |
| Primary indication | |||
| Aneurysm | 285 (66) | 3 (38) | .193 |
| Dissection | 102 (24) | 4 (50) | .189 |
| Valvular | 28 (7) | 0 (0) | .989 |
| Obstruction | 2 (1) | 0 (0) | 1.000 |
| Infection | 10 (2) | 1 (13) | .493 |
| Hematoma | 6 (1) | 0 (0) | 1.000 |
| Urgent or emergent status | 211 (49) | 3 (38) | .780 |
| Operative details | |||
| Ascending only | 12 (3) | 0 (0) | 1.000 |
| Proximal extension | 204 (47) | 1 (13) | .111 |
| VSRR | 84 (19) | 0 (0) | .351 |
| Bentall | 82 (19) | 0 (0) | .364 |
| AV procedure | 38 (9) | 1 (13) | 1.000 |
| Distal extension | 94 (22) | 4 (50) | .141 |
| Hemiarch replacement | 20 (5) | 2 (25) | .072 |
| Partial/total arch replacement | 74 (17) | 2 (25) | .911 |
| Proximal + distal extensions | 122 (28) | 3 (38) | .857 |
| Root + hemiarch | 17 (4) | (0) | 1.000 |
| Root + partial/total arch | 23 (5) | 0 (0) | 1.000 |
| AVR + hemiarch | 42 (10) | 3 (38) | .048† |
| AVR + partial/total arch | 40 (9) | 0 (0) | .778 |
| Additional procedures | |||
| CABG | 76 (18) | 2 (25) | .939 |
| Mitral valve | 29 (7) | 1 (13) | 1.000 |
| Tricuspid valve | 9 (2) | 0 (0) | 1.000 |
| CPB time, min | 180 [143-216] | 219 [131-249] | .372 |
| Crossclamp time, min | 135 [93-164] | 108 [91-155] | .541 |
| Use of circulatory arrest | 219 (50) | 3 (38) | .731 |
| Postoperative outcomes | |||
| Inotropes on ICU admission | 329 (76) | 6 (75) | 1.000 |
| VIS on ICU admission | 4.92 [1.05-9.67] | 10.73 [7.33-13.16] | .191 |
| Length of ICU stay, d | 3.0 [1.6-6.0] | 8.9 [4.7-9.7] | .014† |
| Length of hospital stay, d | 8 [6-14] | 11 [10-16] | .182 |
| Uneventful recovery | 274 (63) | 2 (25) | .063 |
| In-hospital mortality | 9 (2) | 2 (25) | .003† |
| Reexploration for bleed | 21 (5) | 1 (13) | .870 |
| Pacemaker implantation | 29 (7) | 1 (13) | 1.000 |
| Respiratory failure | 122 (28) | 6 (75) | .013† |
| Stroke | 23 (5) | 3 (38) | .002† |
| Acute renal failure | 26 (6) | 1 (13) | .989 |
| Deep sternal infection | 4 (1) | 0 (0) | 1.000 |
| Postcardiotomy shock | 14 (3) | 1 (13) | .655 |
LVEF, Left ventricular ejection fraction; IQR, interquartile range; VSRR, valve-sparing root replacement; AV, aortic valve; AVR, aortic valve replacement; CABG, coronary artery bypass graft; CPB, cardiopulmonary bypass time; ICU, intensive care unit; VIS, vasoactive inotropic score.
∗
n = 5 (63%).
†
P value < .05.