Table E9.
Patient characteristics for isolated aortic disease cohort
| Variable | Isolated aortic disease (n = 110), N (%), median [IQR] | Remaining patients (n = 330), N (%), median [IQR] | P value |
|---|---|---|---|
| Preoperative characteristics | |||
| Age | 60 [50-68] | 61 [51-70] | .367 |
| Female | 32 (29) | 68 (21) | .088 |
| Body surface area | 2.07 [1.91-2.22] | 2.03 [1.87-2.20] | .431 |
| Hypertension | 75 (68) | 250 (76) | .150 |
| On dialysis | 1 (1) | 4 (1) | 1.000 |
| Diabetes | 12 (11) | 49 (15) | .381 |
| Infective endocarditis | 0 (0) | 25 (8) | .006∗ |
| Chronic lung disease | 9 (8) | 48 (15) | .119 |
| Cerebrovascular disease | 5 (5) | 45 (14) | .015∗ |
| Peripheral vascular disease | 23 (21) | 80 (24) | .559 |
| Primary indication | |||
| Aneurysm | 79 (72) | 209 (63) | .132 |
| Dissection | 26 (24) | 80 (24) | 1.000 |
| Valvular | 3 (3) | 25 (8) | .114 |
| Obstruction | 1 (1) | 1 (0) | 1.000 |
| Infection | 1 (1) | 10 (3) | .378 |
| Hematoma | 2 (2) | 4 (1) | 1.000 |
| Urgent or emergent status | 54 (49) | 160 (49) | 1.000 |
| Operative details | |||
| Ascending only | 1 (1) | 11 (3) | .311 |
| Proximal extension | 48 (44) | 157 (47) | .544 |
| VSRR | 35 (32) | 49 (15) | <.001∗ |
| Bentall | 11 (10) | 71 (22) | .011∗ |
| AV procedure | 2 (2) | 37 (11) | .005∗ |
| Distal extension | 34 (31) | 64 (19) | .017∗ |
| Hemiarch replacement | 9 (8) | 13 (4) | .130 |
| Partial/total arch replacement | 25 (23) | 51 (16) | .109 |
| Proximal + distal extensions | 27 (25) | 98 (30) | .360 |
| Root + hemiarch | 9 (8) | 8 (2) | .015∗ |
| Root + partial/total arch | 9 (8) | 14 (4) | .174 |
| AVR + hemiarch | 5 (5) | 40 (12) | .037∗ |
| AVR + partial/total arch | 4 (4) | 36 (11) | .035∗ |
| CPB time, min | 171 [143-197] | 185 [141-226] | .030∗ |
| Crossclamp time, min | 133 [86-165] | 135 [95-164] | .335 |
| Use of circulatory arrest | 49 (45) | 170 (52) | .248 |
| Postoperative outcomes | |||
| Inotropes on ICU admission | 76 (69) | 259 (79) | .061 |
| VIS on ICU admission | 3.14 [0-7.97] | 5.24 [1.23-11.10] | .003∗ |
| Length of ICU stay, d | 2.0 [1.3-5.0] | 3.4 [1.8-6.8] | .006∗ |
| Length of hospital stay, d | 7 [5-12] | 9 [6-14] | .001∗ |
| Uneventful recovery | 87 (79) | 189 (57) | <.001∗ |
| In-hospital mortality | 0 (0) | 11 (3) | .113 |
| Re-exploration for bleed | 2 (2) | 20 (6) | .130 |
| Pacemaker implantation | 2 (2) | 28 (9) | .029∗ |
| Respiratory failure | 18 (16) | 110 (33) | .001∗ |
| Stroke | 4 (4) | 22 (7) | .350 |
| Acute renal failure | 3 (3) | 24 (7) | .136 |
| Deep sternal infection | 1 (1) | 3 (1) | 1.000 |
| Postcardiotomy shock | 0 (0) | 15 (5) | .049∗ |
| Change in LVEF (%) | 0 [−2.5 to 2.5] | 0 [−5 to 4.25] | .501 |
| Decrease in RVSF | 14 (14) | 70 (24) | .054 |
IQR, Interquartile range; VSRR, valve-sparing root replacement; AV, aortic valve; AVR, aortic valve replacement; CPB, cardiopulmonary bypass time; ICU, intensive care unit; VIS, vasoactive inotropic score; LVEF, left ventricular ejection fraction; RVSF, right ventricular systolic function.
∗
P value < .05.