Table 4.

Logistic regression analysis of patients with and without adverse drug reactions

	Univariable OR (95% CI)	P value (Wald χ2)	Multivariable OR (95% CI)	P value (Wald χ2)
Age	1.02 (1.01 to 1.03)	<0.001	1.02 (1.01 to 1.03)	<0.001
Sex (male)	1.07 (0.80 to 1.44)	0.659
Number of medicines	1.11 (1.07 to 1.14)	<0.001	1.10 (1.07 to 1.13)	<0.001
Number of comorbidities	1.08 (1.04 to 1.13)	<0.001
Liver impairment (CLD)	2.58 (1.35 to 4.93)	0.004	3.23 (1.63 to 6.40)	<0.001
Renal impairment (CKD stage IV or V)	1.69 (1.04 to 2.78)	0.036

CKD, chronic kidney disease; CLD, chronic liver disease.