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. 2022 Jun 21;10:901093. doi: 10.3389/fcell.2022.901093

FIGURE 3.

FIGURE 3

The nNOS positive labeled neurons increased at the established hypertension stage (12 weeks) but decreased at the senescence stage (12 months) of SHR as analyzed by nNOS immunoreaction. nNOS positive labeled neurons in the striatum of 12 week-old SHR (A,B) (with an amplificatory image inserted into B) and WKY (C), the hippocampus of 12 week-old SHR (D,E) (with an amplificatory image inserted into E) and WKY (F), the frontal cortex of 12-week-old SHR (G) and WKY (H), the frontal cortex of 12 month-old SHR (I), bar = 100 μm.