Table 3.

Key studies reporting albuminuria or albumin processing dysfunction

Gene, Protein, or Defective Agent/Treatment	Reference(s)
Endogenous or exogenous protein overload	(3)
Megalin-cubilin	(165, 205, 207, 213, 214, 218–222, 224)
Bardoxolone	(217)
NHE-3 (SLC9A3)	(225)
CLC-5	(226, 227, 229)
Rab 38	(230–232)
Statins	(233–235)
Diphtheria toxin-induced PTC injury	(236–238)
d-Serine induced PTC injury	(239)
GWAS: cubilin but also OAF and PRKCI	(251)

GWAS, genomewide association study; PTC proximal tubule cell.